Biografia professionale
Silvia De Rosa è ricercatore di tipo B al Centro di Scienze Mediche – CISMed Università di Trento ed un anestesista e intensivista presso il Dipartimento di Anestesia e Terapia Intensiva dell'Ospedale Regionale Santa Chiara, APSS Trento, Italia. In precedenza, è stata Dirigente Medico di primo livello presso l'Ospedale San Bortolo di Vicenza e Ricercatrice presso l'International Renal Research Institute di Vicenza. Durante la formazione specialistica, ha svolto un periodo di ricerca come research fellow in Medical Simulation presso il Center of Simulation, Advanced Education and Innovation del Children's Hospital di Philadelphia, e ha ottenuto una Clinical and Research Fellowship in Critical Care Nephrology presso l'International Renal Research Institute di Vicenza (IRRIV), Dipartimento di Nefrologia, Dialisi, Trapianto dell'Ospedale San Bortolo, Vicenza. Ha conseguito l'abilitazione Scientifica Nazionale nel settore concorsuale 06/L1 Anestesiologia - Fascia: II (2019-2030) e Fascia: I (2023-2034).
Attività e interessi di ricerca
Autrice di 107 articoli in extenso in peer reviewed su riviste internazionali (Scopus; ISI Web della Scienza, PubMed). H-Index 23.
I suoi campi di interesse includono il Danno Renale Acuto, le tecniche di Supporto d’Organo Extracorporeo, la Nutrizione e il Wasting Muscolare, la Gestione delle Vie Aeree, il Trauma Maggiore, e la Medicina Genere in Terapia Intensiva.
Collaborazioni
Società Scientifiche:
- European Society of Intensive Care Medicine
- Società Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva (SIAARTI)
- International Society of Nephrology (ISN)
Gruppi di Lavoro e Commissioni:
- Acute Quality Dialysis Initiative Group
- Joint commission of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care - Italian Society of Nephrology
- Consensus Multisocietaria - Sindrome Emolitico-Uremica Atipica
Principali collaborazioni in corso:
Claudio Ronco, Italia
John Prowle, Regno Unito
Rinaldo Bellomo, Australia
Michael Joannidis, Austria
Marlies Ostermann, Regno Unito
Alexander Zarbock, Germania
Stefan Schaller, Germania
Denise Battaglini, Italia
Chiara Robba, Italia
Michele Umbrello, Italia
Marco Fiorentino, Italia
Marita Marengo, Italia
Vincenzo Cantaluppi, Italia
Baibre McNicholas, Irlanda
Max Bell, Svezia
Thomas Rimmelè, Francia
Eric Hoste, Belgio
Ricard Ferrer; Spagna
Massimiliano Sorbello, Italia
Pubblicazioni scelte
Zarbock A, Nadim MK, Pickkers P, Gomez H, Bell S, Joannidis M, Kashani K, Koyner JL, Pannu N, Meersch M, Reis T, Rimmelé T, Bagshaw SM, Bellomo R, Cantaluppi V, Deep A, De Rosa S, Perez-Fernandez X, Husain-Syed F, Kane-Gill SL, Kelly Y, Mehta RL, Murray PT, Ostermann M, Prowle J, Ricci Z, See EJ, Schneider A, Soranno DE, Tolwani A, Villa G, Ronco C, Forni LG. Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup. Nat Rev Nephrol. 2023 Jun;19(6):401-417. doi: 10.1038/s41581-023-00683-3. Epub 2023 Feb 23. PMID: 36823168.
Merdji H, Long MT, Ostermann M, Herridge M, Myatra SN, De Rosa S, Metaxa V, Kotfis K, Robba C, De Jong A, Helms J, Gebhard CE. Sex and gender differences in intensive care medicine. Intensive Care Med. 2023 Oct;49(10):1155-1167. doi: 10.1007/s00134-023-07194-6. Epub 2023 Sep 7. PMID: 37676504; PMCID: PMC10556182.
De Rosa S, Cutuli SL, Lorenzin A, Zanella M. Sequential Extracorporeal Therapy in Sepsis. Contrib Nephrol. 2023;200:149-159. doi: 10.1159/000527573. Epub 2023 Jun 8. PMID: 37290408.
von Groote T, Meersch M, Romagnoli S, Ostermann M, Ripollés-Melchor J, Schneider AG, Vandenberghe W, Monard C, De Rosa S, Cattin L, Rahmel T, Adamzik M, Parise D, Candela-Toha A, Haaker JG, Göbel U, Bernard A, Lumlertgul N, Fernández-Valdes-Bango P, Romero Bhathal I, Suarez-de-la-Rica A, Larmann J, Villa G, Spadaro S, Wulf H, Arndt C, Putensen C, García-Álvarez R, Brandenburger T, Siniscalchi A, Ellerkmann R, Espeter F, Porschen, Sadjadi M, Saadat-Gilani K, Weiss R, Gerss J, Kellum J, Zarbock A; BigpAK-2 Investigators. Biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2 trial): study protocol for an international, prospective, randomised controlled multicentre trial. BMJ Open. 2023 Mar 27;13(3):e070240. doi: 10.1136/bmjopen-2022-070240. PMID: 36972972; PMCID: PMC10069589.
De Rosa S, Battaglini D, Robba C. Kidney dysfunction after Acute Brain Injury. Nephrol Dial Transplant. 2023 Sep 2:gfad192. doi: 10.1093/ndt/gfad192. Epub ahead of print. PMID: 37660284.
De Rosa S, Battaglini D, Bennett V, Rodriguez-Ruiz E, Zaher AMS, Galarza L, Schaller SJ; NEXT Committee of the ESICM. Key steps and suggestions for a promising approach to a critical care mentoring program. J Anesth Analg Crit Care. 2023 Aug 29;3(1):30. doi: 10.1186/s44158-023-00116-4. PMID: 37644586; PMCID: PMC10464173.
Pistolesi V, Morabito S, Pota V, Valente F, Di Mario F, Fiaccadori E, Grasselli G, Brienza N, Cantaluppi V, De Rosa S, Fanelli V, Fiorentino M, Marengo M, Romagnoli S; SIAARTI-SIN joint commission. Regional citrate anticoagulation RCA) in critically ill patients undergoing renal replacement therapy (RRT): expert opinion from the SIAARTI-SIN joint commission. J Anesth Analg Crit Care. 2023 Mar 31;3(1):7. doi: 10.1186/s44158-023-00091-w. PMID: 37386664; PMCID: PMC10245563.
Reis T, Ronco C, Soranno DE, Clark W, De Rosa S, Forni LG, Lorenzin A, Ricci Z, Villa G, Kellum JA, Mehta R, Rosner MH; Nomenclature Standardization Faculty. Standardization of Nomenclature for the Mechanisms and Materials Utilized for Extracorporeal Blood Purification. Blood Purif. 2023 Sep 13:1-14. doi: 10.1159/000533330. Epub ahead of print. PMID: 37703868.
Cotoia A, Umbrello M, Ferrari F, Pota V, Alessandri F, Cortegiani A, De Rosa S. Nutritional support and prevention of post-intensive care syndrome: the Italian SIAARTI survey. J Anesth Analg Crit Care. 2023 Nov 7;3(1):45. doi: 10.1186/s44158-023-00132-4. PMID: 37936182; PMCID: PMC10631207.
Forin E, Lorenzoni G, Ferrer R, De Cal M, Zanella M, Marchionna N, Gregori D, Forfori F, Lorenzin A, Danzi V, Ronco C, De Rosa S. Endotoxin removal therapy with Polymyxin B immobilized fiber column: a single center experience from EUPHAS2 registry. Sci Rep. 2023 Oct 16;13(1):17600. doi: 10.1038/s41598-023-44850-9. PMID: 37845296; PMCID: PMC10579294.
De Rosa S, Marengo M, Fiorentino M, Fanelli V, Brienza N, Fiaccadori E, Grasselli G, Morabito S, Pota V, Romagnoli S, Valente F, Cantaluppi V; SIAARTI-SIN joint commission. Extracorporeal blood purification therapies for sepsis-associated acute kidney injury in critically ill patients: expert opinion from the SIAARTI-SIN joint commission. J Nephrol. 2023 Sep;36(7):1731-1742. doi: 10.1007/s40620-023-01637-5. Epub 2023 Jul 13. PMID: 37439963; PMCID: PMC10543830.
Cutuli SL, De Rosa S, Ferrer R, Ruiz-Rodriguez JC, Forfori F, Ronco C, Antonelli M; EUPHAS2‐G50 Collaborative Study Group. Endotoxin activity trend and multi-organ dysfunction in critically ill patients with septic shock, who received Polymyxin-B hemadsorption: A multicenter, prospective, observational study. Artif Organs. 2023 Aug;47(8):1361-1370. doi: 10.1111/aor.14534. Epub 2023 Apr 27. PMID: 37767775.
Greco M, De Rosa S, Boehm F, Spano S, Aceto R, Voza A, Reggiani F, Calatroni M, Castellani G, Costantini E, Villa G, Cecconi M. Kinetics of the Cell Cycle Arrest Biomarkers (TIMP2 and IGFBP7) for the Diagnosis of Acute Kidney injury in Critically Ill COVID-19 Patients. Diagnostics (Basel). 2023 Jan 15;13(2):317. doi: 10.3390/diagnostics13020317. PMID: 36673127; PMCID: PMC9857893.
De Rosa S, Zanella M, Samoni S, Ronco C. Endotoxin removal therapy with Polymyxin B immobilized fiber column as a COVID-19-bedside strategy protocol for endotoxic shock. Front Nephrol. 2022 Aug 3;2:847305. doi: 10.3389/fneph.2022.847305. PMID: 37675016; PMCID: PMC10479594.
De Rosa S, Marengo M, Romagnoli S, Fiorentino M, Fanelli V, Fiaccadori E, Brienza N, Morabito S, Pota V, Valente F, Grasselli G, Messa P, Giarratano A, Cantaluppi V. Management of Acute Kidney Injury and Extracorporeal Blood Purification Therapies During the COVID-19 Pandemic: The Italian SIN-SIAARTI Joint Survey (and Recommendations for Clinical Practice). Front Med (Lausanne). 2022 Apr 7;9:850535. doi: 10.3389/fmed.2022.850535. PMID: 35463000; PMCID: PMC9021595.
Golino G, Greco M, Rigobello A, Danzi V, De Cal M, Malchiorna N, Zannella M, Navalesi P, Costa-Pinto R, Ronco C, De Rosa S. Incidence of Acute Kidney Injury in Polytrauma Patients and Predictive Performance of TIMP2 × IGFBP7 Biomarkers for Early Identification of Acute Kidney Injury. Diagnostics (Basel). 2022 Oct 13;12(10):2481. doi: 10.3390/diagnostics12102481. PMID: 36292170; PMCID: PMC9601128.
De Rosa S, Cutuli SL, Ferrer R, Antonelli M, Ronco C; COVID-19 EUPHAS2 Collaborative Group. Polymyxin B hemoperfusion in coronavirus disease 2019 patients with endotoxic shock: Case series from EUPHAS2 registry. Artif Organs. 2021 Jun;45(6):E187-E194. doi: 10.1111/aor.13900. Epub 2021 Feb 17. PMID: 33377184.
Samoni S, Villa G, De Rosa S, Husain-Syed F, Guglielmetti G, Tofani L, De Cal M, Nalesso F, Meola M, Ronco C. Ultrasonographic Intraparenchymal Renal Resistive Index Variation for Assessing Renal Functional Reserve in Patients Scheduled for Cardiac Surgery: A Pilot Study. Blood Purif. 2022;51(2):147-154. doi: 10.1159/000516438. Epub 2021 May 27. PMID: 34044391.
Godi I, De Rosa S, Martino F, Bazzano S, Martin M, Boni E, Carta MR, Tamayo Diaz C, Mari G, Lorenzin A, de Cal M, Corradi V, Caprara C, Giavarina D, Ronco C. Urinary [TIMP-2] × [IGFBP7] and serum procalcitonin to predict and assess the risk for short-term outcomes in septic and non-septic critically ill patients. Ann Intensive Care. 2020 Apr 21;10(1):46. doi: 10.1186/s13613-020-00665-9. PMID: 32318859; PMCID: PMC7174532.
De Rosa S, Messina A, Sorbello M, Rigobello A, Colombo D, Piccolo A, Bonaldi E, Gennaro P, Urukalo V, Pellizzari A, Bonato R, Carboni SC. Laryngeal Mask Airway Supreme vs. the Spritztube tracheal cannula in anaesthetised adult patients: A randomised controlled trial. Eur J Anaesthesiol. 2019 Dec;36(12):955-962. doi: 10.1097/EJA.0000000000001106. PMID: 31644512.